The involvement of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in atherosclerosis
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چکیده
منابع مشابه
The involvement of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in atherosclerosis.
OBJECTIVES Herein, we determined the significance of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in atherosclerotic vascular disease. BACKGROUND Inflammation is associated with the pathogenesis of atherosclerosis. The TNF-related apoptosis-inducing ligand/APO-2L, a member of the TNF superfamily, has a role in apoptosis induction and is recognized for its immunomodula...
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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been reported to specifically kill malignant cells but to be relatively nontoxic to normal cells. To evaluate the antitumor activity and therapeutic value of the TRAIL gene, we constructed adenoviral vectors expressing the human TRAIL gene and transferred them into malignant cells in vitro and tumors in vivo. The in vitro trans...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2005
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2004.12.065